Leadership Team

TISH utilizes a model that allows us to collaborate the finest innovators in the world. The TISH Leadership team manages the day-to-day activities (project management) of the lab, while much of the actual work done in the lab is performed by member organizations, partners and affiliates. For example, if a project calls for a team with a very specific expertise, TISH draws from it's partners and affiliates (as well as the community) to bring together the perfect team for the project. This allows us to maintain a lean staff while employing the greatest minds in the world.

Brett E Trusko, DBA, MBA


Brett E Trusko, DBA is a founder of TISH and a member of the Board of Directors. His goals for TISH are simply to "change the way health care is delivered" throughout the world. He has 25 years experience as a health care consultant and Managing Director with one of the largest consultancies in the world. He also has six years experience in academic medicine, serving on faculty at the Mayo Clinic, Mount Sinai School of Medicine at NYU and at Baylor College of Medicine. He is the author of Improving Healthcare Cost and Quality with Six Sigma,and is the Editor-in-Chief of the International Journal of Innovation Science. ( He is an internationally recognized speaker as a futurist and innovation expert. He is a Fellow at HIMSS and has numerous other professional certifications.

DeLeys Brandman, M.D., M.P.H.

Senior Vice President, Strategic Projects

Dr. Brandman has worked in health care both as a provider and as a management consultant to providers, payers, and life science companies for more than 20 years. She is trained and board certified as a primary care internist, an emergency medicine physician, and a corporate medicine/preventive medicine specialist, and received a Master's degree in Public Health from the University of California, Berkeley. She has used this broad base of education and experience to work in all segments of health care to design and implement solutions, build new processes for transitions of care, and build e-business solutions with providers, MHO's, insurers, hospital systems, consumers, and employers. She has deep experience with the development and use of Bioinformatics and the information systems required to support metric driven care.

Today, she is focused on supporting the consumer to take a proactive role in understanding and maintaining their health and well being. She is actively involved with technologies and social media tools to expand their use in engaging the consumer and improving the quality and cost effectiveness of the health care system at the level of the individual.

Jack Smith, M.D., PhD


Dr. Jack W. Smith was recruited from Ohio State University to become the first Chairman of the Department of Health Informatics at the University of Texas Health Science Center at Houston, where he serves as Dean from 2003-2012. He is a former Deputy Director of Medical Informatics and Healthcare Systems at the National Aeronautics and Space Administration (NASA) - Johnson Space Center, Houston. He was instrumental in establishing the Center for Clinical and Translational Sciences in partnership with The University of Texas Health Science Center at Houston, MD Anderson Cancer Center, and the Memorial Hermann Hospital System.

Today his research and commercial interests are focused on artificial intelligence, modeling complex problem-solving in health care, implementation of decision support and tutoring systems, and the application of cognitive science to understanding human-computer interaction. Dr. Smith is a board certified in Pathology and has a doctorate in Computer Science in the area of Artificial Intelligence.

Harry Holmes, PhD

Interim Chairman of the Board

Harry Holmes brings long experience with healthcare, the Texas Medical Center institutions, and the greater Houston healthcare community to TISH. Harry was the VP of Government Relations at the MD Anderson Cancer Center, before moving to an executive position in the Texas Medical Center. At TMC, he was the SVP, Public Affairs and Government Relations, where he represented the interests of institutions across the Medical Center. He received his BA in economics from Rice, and his PhD in American Urban Studies from the American University of Missouri-Columbia.

Praveen Gupta, M.S.E.E.

Training Director

In addition to his position as Training Director at TISH, Praveen Gupta is the Director of the Center for Innovation Science and Applications at IIT School of Applied Technology and a visiting lecturer at The University of Illinois, Chicago. His Innovation curriculum is taught at multiple institutions in the U.S. and Mexico.

Praveen is the author of  Business Innovation in the 21st Century, The Innovation Solution, Service Scorecard, Six Sigma Business Scorecard, Stat Free Six Sigma, and the Six Sigma Performance Handbook and the founding Editor of the International Journal of Innovation Science, and has pioneered deployment of the Six Sigma methodology as a Certified Six Sigma Master Black Belt and a Certified Professional Engineer.

Lisa Friedman, PhD, Managing Partner, Enterprise Development Group

Founding Advisor

Lisa Friedman, Ph.D. is the managing partner of the Enterprise Development Group and co-author of The Dynamic Enterprise: Tools for Turning Chaos into Strategy and Strategy into Action. She most often consults to organizations whose industries are in the midst of complex change,to facilitate a shared understanding of the emerging trends transforming their industry, to shape vision and strategy for the future, to teach simple but powerful innovation practices, and to align organizations to realize their goals. She is an educator on innovation strategy, innovation best practices and tools, future-driven leadership, and sustainable enterprise. Her clients include a mix of healthcare organizations, hospitals and medical centers, physician groups, and health technology companies, as well as global high-tech companies, media companies, and start-ups.